A dominant yet wasteful Real ravaged their rivals in the first half while spurning a string of clear chances at the Santiago Bernabeu.
Real Madrid barged their way back into the Spanish La Liga title race with a 3-1 victory over Atletico Madrid in a feisty derby at the Wanda Metropolitano on Saturday.
Karim Benzema scored twice after the interval with a penalty and a header from a corner to give Santiago Solari's side a 3-1 lead, after Raphael Varane struck in the 34th minute to cancel out Anuar Tuhami's goal for Valladolid five minutes earlier.
Revolution is in the air at Real Madrid after their Champions League empire was razed to the ground with an astounding 4-1 loss at home to Ajax Amsterdam, with a huge clear out of players expected as well as a change of manager.
Here are five talking points from the weekend's action in Spain.
It compounded a woeful few months for the club as coach Julen Lopetegui came and went before former player Santiago Solari replaced him in November. They sat sixth in La Liga and appeared a team in decline, sorely missing forward Cristiano Ronaldo, who left for Juventus last summer.
La Liga leaders Barcelona earned a narrow 1-0 win over Real Valladolid to move seven points clear at the top, while Real Madrid lost 2-1 at home against Girona to fall to third behind Atletico Madrid.
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Midfielder Santi Cazorla gave the home side the lead in the fourth minute of the game, which was rescheduled due to Real's participation in last month's Club World Cup, by bending a wonderful shot into the bottom corner.
Madrid won only two of their seven pre-season games
Atletico Madrid crashed out of the Copa del Rey to Girona on Wednesday following a highly entertaining 3-3 draw at home to the Catalan side, who sneaked through to the quarter-finals on away goals after the tie finished 4-4 on aggregate.
Holders Real Madrid were sensationally knocked out of the Champions League on Tuesday after being thrashed 4-1 at home by an outstanding Ajax Amsterdam who overturned a first-leg deficit to reach the quarter-finals 5-3 on aggregate.
Zinedine Zidane has been reappointed as Real Madrid coach nine months after resigning, replacing Argentine Santiago Solari.
La Liga leaders Barcelona moved 10 points clear with a 4-1 win at Real Betis on Sunday after second place Atletico Madrid slipped up at Athletic Bilbao on Saturday in a 2-0 defeat.
Ajax, four-times European Cup winners who are in the knockout stages for the first time in 13 years, have enhanced their reputation as a talent factory due to the rise of homegrown Dutch players Frenkie de Jong and Matthijs de Ligt.
Ousmane Dembele's late strike rescued a 1-1 draw for champions Barcelona at Atletico Madrid but Sevilla moved top with a 1-0 win over Real Valladolid. European champions Real Madrid were humiliated in a 3-0 defeat at Eibar.
La Liga leaders Barcelona hit two goals in the final three minutes to earn a 3-2 win at Rayo Vallecano
Here are five talking points from the weekend in La Liga:
Here are five talking points from the weekend's action in La Liga.
IMAGES from the La Liga matches played on Sunday
'Cristiano scored 50 goals and you can't find someone today who scores that many. Some of us have to take a step forward and, while not scoring 50, what we need is two or three players who score 15, 20, or 10 goals and we don't have that.'
Midfielder Dani Ceballos added: "It looks like us changing our coach worked. We have recovered some sensations we had lost and we have got the three points. Now our objective is to win all the games left and finish the season as well as possible."
News of all that's transpired on and off the football field
La Liga leaders Barcelona won a tight and tense 'Clasico' 1-0 at Real Madrid on Saturday, beating their great rivals at their Bernabeu home for the second time in four days and moving a staggering 12 points clear of them in the standings.
News of all that's transpired on and off the football field
Former Real Madrid striker Predrag Mijatovic criticised Gareth Bale for lacking leadership qualities
Portugal international Goncalo Guedes fired Valencia into the lead in the 35th minute with a thumping shot from inside the area which was too powerful for Madrid goalkeeper Keylor Navas.
Despite their first-leg advantage, Pochettino warned against complacency and said he wanted his team to play for another win, although they have had one day less to prepare than the Germans.
News of all that's transpired on and off the football field
Federico Valverde has already made over 100 appearances at senior level - while winning silverware and recognition both with his current side Madrid and country Uruguay, and showing the physical, technical and mental attributes to become one of world football's outstanding midfielders.
News of all that's transpired on and off the football field
Leeds United manager Marcelo Bielsa asked his players to allow the visitors to score unchallenged when the game was restarted.
Griezmann special earns Atletico 1-1 draw at Sevilla
Karim Benzema scored his sixth goal in four games as Real Madrid beat Alaves 3-0 on Sunday for a fourth successive La Liga victory which took the European champions to within eight points of leaders Barcelona.
Karim Benzema netted a second-half hat-trick as Real Madrid got back to winning ways with a 3-0 victory over Athletic Bilbao in La Liga on Sunday.
IMAGES from La Liga matches played on Sunday
Images from the Champions League matches played on Wednesday
An insatiable Lionel Messi scored for the eighth game in a row in all competitions as La Liga champions Barcelona saw off a gutsy Girona side 2-0 to go five points clear at the top of the standings.
News of all that's transpired on and off the football field
A round-up of Saturday's action in La Liga, Ligue 1 and Serie A.